Polycystic ovaries after precocious pubarche: relation to prenatal growth

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Polycystic ovaries after precocious pubarche: relation to prenatal growth.

BACKGROUND In 1998, we revealed a sequence departing from prenatal growth restraint in girls and evolving, through precocious pubarche (PP) in mid-childhood, towards anovulatory and hyperinsulinaemic hyperandrogenism. The latter condition fulfilled the criteria for the diagnosis of polycystic ovary syndrome (PCOS), which was then defined independently of the presence of polycystic ovaries (PCOs...

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Precocious pubarche in Thai children.

OBJECTIVE To describe the etiologies, clinical characteristics, and laboratory investigations of young Thai children being evaluated for precocious pubarche. MATERIAL AND METHOD The medical records of 41 children referred for evaluation of precocious presence of pubic hair at Songklanagarind Hospital between 1995 and 2011 were retrospectively reviewed. RESULTS The etiologies of precocious p...

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Bilateral Polycystic Ovaries.

The writing of an article about this condition presents considerable difficulties. It is found in a numbet of separate disorders and is not therefore an entity in itself, though a common final mechanism may be typically involved. Moreover, a number of matters are involved about which knowledge is confused, fragmentary or uncertain. It is proposed to consider various aspects of the subject separ...

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ENVIRONMENTAL FACTORS AND POLYCYSTIC OVARIES

This study was designed to investigate the effect of environmental factors on the appearance of polycystic ovaries (PCO) during the first two decades of life. Ninety-four female-female twins who underwent a transabdominal ultrasound at the Royal Hospital for Women were sent a questionnaire asking about their birth details, feeding history as a baby, childhood illnesses and vaccination as w...

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Polycystic ovary syndrome resembling histopathological alterations in ovaries from prenatal androgenized female rats

BACKGROUND The polycystic ovary syndrome (PCOS) affects approximately 6-10% of women of reproductive age and is characterized by chronic anovulation and hyperandrogenism. However, a comprehensive understanding of the mechanisms that dictate androgen overproduction is lacking, which may account for inconsistencies between measures of androgen excess and clinical presentation in individual cases....

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2006

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/del395